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" Russia's Soyuz MS-04 spacecraft blasts off from the launch pad at Baikonur cosmodrome in Kazakhstan on April 20 Jeff Petry Jersey , 2017. Russia on Thursday successfully launched its Soyuz MS-04 spacecraft carrying two astronauts to the International Space Station (ISS), the Russian State Space Corporation Roscosmos said. (XinhuaMikheev)
MOSCOW, April 20 (Xinhua) -- Russia on Thursday successfully launched its Soyuz MS-04 spacecraft carrying two astronauts to the International Space Station (ISS), the Russian State Space Corporation Roscosmos said.


The launch of the Soyuz-FG carrier rocket with the spacecraft took place at 10:13 a.m. Moscow time (0713 GMT) from the Baikonur cosmodrome in Kazakhstan, Roscosmos said.


The two men aboard the spacecraft are Russian cosmonaut Fyodor Yurchikhin and U.S. National Aeronautics and Space Administration's (NASA) astronaut Jack Fischer. They are expected to spend 136 days in space this time.


The docking of the spacecraft is scheduled for 04:23 p.m. Moscow time (1323 GMT), Roscosmos said.


The launch was initially scheduled for March 27, but was delayed for more safety checks.



" "

Downton Abbey could be getting a little more rock 'n' roll.


The Rolling Stones Phillip Danault Jersey , according to a report in the UK's Guardian, could appear on an episode of Downton Abbey if one star gets his wish, an unnamed source tells the newspaper.


Downton's Hugh Bonneville, aka the Earl of Grantham, is friends with the Stones' Ronnie Wood through charity work and would love to have the band members on for walk-on roles. ""Obviously they wouldn't play themselves, but they could be a rag-tag bunch of travelling entertainers or even a circus act,"" the source says. ""It would be such a coup Karl Alzner Jersey , and fun for the Stones. They really are huge fans of the show.""


And although there's no word (yet) if the Stones are interested in going period, they're huge fans of the show. Laura Carmichael, who plays the lovelorn Lady Edith, says: ""Apparently they were stopping rehearsals on Sunday nights in time to get back to watch it ... When Sybil passed away, Mick [Jagger] said to Ronnie [Wood], 'Sad to hear about the girl.' Ronnie replied, 'I haven't seen it yet — I recorded it.'""


Agencies

" "

SAN FRANCISCO Jonathan Drouin Jersey , March 17 (Xinhua) -- In what could lead to contraceptives that work in both men and women, researchers at University of California, Berkeley, have identified a protein receptor on the surface of sperms that responds to the female sex hormone progesterone.


Describing the receptor as a switch, or a trigger, the researchers said it is the key to the ""power kick"" needed by a sperm to penetrate and fertilize a human egg.


""If the receptor protein doesn't recognize progesterone, you would be infertile Carey Price Jersey ,"" said Melissa Miller, a postdoctoral fellow at both UC Berkeley and University of California, San Francisco, and the first author of a paper published on Thursday in the ""Fast Release"" issue of the journal Science.


Progesterone is released by the egg or oocyte, the ultimate goal toward which sperm swim. When the sperm gets close to the egg, the hormone activates the receptor and triggers a cascade of changes that make the tail snap like a whip, powering the sperm into and hopefully through the cells protecting the egg.


The receptor ""gives us an understanding of another pathway that is involved in human sperm activity Shea Weber Jersey ,"" Miller said, adding that ""what's really cool is that we have an actual target for unisex contraceptive development.""


""If you can stop progesterone from inducing a power stroke, sperm are not going to be able to reach or penetrate the oocyte,"" she explained.


The new discovery has also uncovered a possible source of male infertility, as sperm may be to blame in half of all cases of infertile couples, while doctors currently are unable to determine the cause of nearly 80 percent of all cases of male infertility.


In their lab work, techniques that Polina Lishko Throwback Montreal Canadiens Jerseys , a UC Berkeley assistant professor of molecular and cell biology, and her colleague Yuriy Kirichok developed over the past five years at UCSF and UC Berkeley were used, allowing them to stick electrodes on a sperm's tail and record its reactions to hormones.


That led to their discovery that a large receptor on sperm tails -- a calcium channel dubbed CatSper -- is activated by progesterone from the egg. Progesterone unlocks the channel gate, letting electrically charged calcium atoms flood into the cell, leading to a biochemical cascade that readies the sperm cell for its last-ditch effort to fertilize the oocyte.


Miller and Lishko, senior author of the paper, suspected that progesterone was not acting directly on the calcium channel Custom Montreal Canadiens Jerseys , but on some other receptor that activated the calcium channel.


The team did confirm that progesterone actually binds to a previously mysterious enzyme called ABHD2, which is found at high levels in sperm. Once progesterone binds to the enzyme, which sits on the surface of the sperm, it removes a lipid (2AG) that has been inhibiting the calcium channel. Released of inhibition, CatSper opens the gate to calcium ions and eventual sperm activation.


The inhibitor of CatSper is probably there for a good reason: to prevent sperm from prematurely sprinting toward the egg and using up their limited supply of energy, Miller said.

"

TIANJIN, Dec. 21 (Xinhua) -- A Chinese leasing firm has signed a deal worth 78 billion yuan (12 billion U.S. dollars) with a Chinese-owned Swedish vehicle company Authentic Montreal Canadiens Jerseys , according to National Modern Energy Holdings (NMEH) on Monday.


NMEH is jointly invested and founded by Chinese and Swedish companies. Its Swedish investing party, National Electric Vehicle Sweden (NEVS), will produce 150,000 electric vehicles to China's leasing company Panda New Energy based on Saab 9-3 sedan-platform by the end of 2020.


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